Drug intelligence / Profile preview

cannabidiol implant

Development stage
Preclinical
Lead developer
Qualthera Pharmaceuticals
Modality
Small Molecules
Administration
Implant, Subcutaneous
01

Overview

The cannabidiol implant is a patent-pending, biodegradable, long-acting subcutaneous delivery system developed by Qualthera Pharmaceuticals. Utilizing cannabidiol (CBD) as its active pharmaceutical ingredient, the implant is designed to provide sustained therapeutic levels of CBD over an extended period, addressing the low bioavailability and inconsistent absorption associated with oral and topical administration. The drug's mechanism involves the modulation of cannabinoid receptors (CB1 and CB2), antagonism of GPR55, and agonism of the 5-HT1A receptor. It is currently in early-stage development for the treatment of chronic pain and neurodegenerative conditions, specifically Alzheimer's disease and Parkinson's disease.

Other names
CBD implant
02

Targets

HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))GPR55 (G protein-coupled receptor 55)CNR2 (Cannabinoid receptor type 2)

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