Drug intelligence / Profile preview

cannabinolic acid

Development stage
Preclinical
Lead developer
CNBX Pharmaceuticals
Modality
Small Molecules
01

Overview

Cannabinolic acid is a naturally occurring **small molecule cannabinoid acid** found in cannabis and generally regarded as an oxidative, aromatic degradation product related to tetrahydrocannabinolic acid. It is chemically unstable and readily decarboxylates or otherwise converts to **cannabinol**, which has limited direct development as a distinct pharmaceutical agent. Published literature suggests exploratory bioactivity including potential anticancer, anti-inflammatory, analgesic, antiemetic, anxiolytic, and antidepressant effects, but its **primary pharmacology, molecular targets, and therapeutic mechanism remain insufficiently defined**. Based on the available information, cannabinolic acid appears to be an early-stage research compound rather than a clinically established drug, with no clear evidence of approved products, formal clinical development programs, or standardized manufacturers specific to the isolated molecule.

Other names
cannabinolic acidCBNA

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