Drug intelligence / Profile preview

cannabis flos

Development stage
Unknown
Lead developer
Bedrocan
Administration
Inhalation
01

Overview

Cannabis flos refers to the standardized, dried female inflorescences of the *Cannabis sativa* plant, utilized as a medicinal herbal preparation and a research compound in clinical studies. Its primary psychoactive component is delta-9-tetrahydrocannabinol (THC), which functions as a partial agonist at the cannabinoid type 1 (CB1) and type 2 (CB2) receptors within the endocannabinoid system. In the context of research at Leiden University, cannabis flos has been investigated for its effects on the dopaminergic system and its subsequent impact on creative thinking processes, specifically divergent and convergent thinking. The preparation is typically administered via inhalation using a medical-grade vaporizer to ensure precise and reproducible delivery of cannabinoids. As a botanical product, it contains a complex profile of cannabinoids and terpenes that contribute to its overall pharmacological effect.

Brand names
BedrocanBedrobinolBediolBedica
Other names
cannabis flowermarijuana flowerdried cannabis flower
02

Targets

HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))CNR1 (Cannabinoid receptor 1)FAAHGPR18 (G protein-coupled receptor 18)GPR55 (G protein-coupled receptor 55)MGLL (Monoacylglycerol lipase)PPARG (Peroxisome proliferator-activated receptor gamma)TRPV1 (Transient receptor potential cation channel subfamily V member 1)

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