Drug intelligence / Profile preview

cannabis liquid plant extract

Development stage
Unknown
Lead developer
Jazz Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

Cannabis liquid plant extract is a standardized medical cannabis formulation containing equal concentrations (10 mg/ml) of Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD). This 1:1 ratio is designed to provide therapeutic relief while utilizing CBD to mitigate the psychoactive effects typically associated with THC. The extract is primarily investigated for the management of chronic pain conditions, such as fibromyalgia syndrome, where it aims to modulate the endocannabinoid system to reduce pain severity, improve sleep quality, and decrease joint stiffness. THC acts as a partial agonist at cannabinoid receptors (CB1 and CB2), while CBD acts as a negative allosteric modulator of these receptors and interacts with various other targets including TRPV1 and serotonin receptors.

Other names
medical cannabisMCstandardized MC formulation
02

Targets

CNR2 (Cannabinoid receptor type 2)

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