Drug intelligence / Profile preview

cannabis sativa crude extract

Development stage
Preclinical
Lead developer
University of Johannesburg
Administration
Oral, Topical, Inhalation, Rectal, Sublingual, Buccal, Transdermal
01

Overview

Cannabis sativa crude extract is a botanical preparation derived from the leaves of the *Cannabis sativa* plant, typically obtained through ethanol extraction. In preclinical studies, particularly in pancreatic cancer models like Mia-PaCa2, the crude extract has demonstrated potent anti-cancer activity by triggering programmed cell death. Its mechanism of action involves the modulation of the BCL-2 family of proteins and the activation of the intrinsic apoptotic pathway, leading to DNA fragmentation and cell death. Research indicates that the crude extract may be more effective than isolated cannabinoids like cannabidiol (CBD) due to potential synergistic effects between its various phytochemical components.

Other names
Cannabis sativa extractcrude Cannabis sativa extract
02

Targets

CASP7 (Caspase-7)BAX (Apoptosis regulator BAX)TP53 (Cellular Tumor Antigen p53 R175H)CASP3 (Caspase-3)

Beyond the preview

Go deeper on cannabis sativa crude extract.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on cannabis sativa crude extract.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call