cannabis-UMC Utrecht

Cannabis-UMC Utrecht refers to the specific cannabis preparations used in clinical research conducted by the University Medical Center Utrecht (UMC Utrecht). In a Phase 1 clinical trial (NCT00122616), researchers investigated the pharmacokinetics and physiological effects of smoking cannabis cigarettes of varying strengths. The primary active components of cannabis are cannabinoids, most notably delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC acts as a partial agonist at the Cannabinoid receptor 1 (CB1), located primarily in the central nervous system, and the Cannabinoid receptor 2 (CB2), found mainly in immune cells. The UMC Utrecht study specifically focused on the processing of cannabis and its subsequent effects on the cardiovascular and central nervous systems at higher levels of exposure.

Other names

cannabismarijuanacannabis cigarettes