Drug intelligence / Profile preview

Cannabixir

Development stage
Preclinical
01

Overview

Cannabixir is an EU-GMP certified Cannabis sativa L. product, specifically "Medium Flos". It is being investigated for its therapeutic potential in Alzheimer's disease due to its role as a cannabinoid receptor ligand. Preclinical studies in APP/PS1 mice have shown that chronic intermittent exposure to Cannabixir can reduce anxiety-like behavior, partially reverse cognitive deficits, decrease Aβ plaque deposits, reduce cerebral glucose metabolism, and modulate the expression of mTOR and CB2 receptors, as well as M1 mAChR. These findings highlight its impact on the expanded endocannabinoid system and its potential neuroprotective and cognitive-enhancing effects.

Brand names
Cannabixir Medium Flos
02

Targets

CNR1 (Cannabinoid receptor 1)

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