Drug intelligence / Profile preview

CannAmide + MEAI

Development stage
Preclinical
Lead developer
SciSparc
Modality
Small Molecules
Administration
Oral
01

Overview

CannAmide + MEAI is a proprietary combination therapy being developed through a collaboration between SciSparc Ltd. and Clearmind Medicine Inc. The treatment consists of CannAmide™, a formulation of the anti-inflammatory fatty acid amide palmitoylethanolamide (PEA), and MEAI (5-methoxy-2-aminoindane), a non-hallucinogenic psychedelic molecule. This combination is designed to leverage the synergistic effects of its components to address complex conditions such as alcohol use disorder, cocaine addiction, obesity, and depression. Preclinical studies have demonstrated that the combination can effectively reduce alcohol consumption, suppress drug cravings, and promote weight loss by increasing energy expenditure and reducing appetite. The therapy is currently in preclinical development, with patent applications filed for various therapeutic uses.

Other names
palmitoylethanolamide + 5-methoxy-2-aminoindanePEA + MEAI
02

Targets

PPARA (Peroxisome proliferator-activated receptor alpha)

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