Drug intelligence / Profile preview

CannaXan 701-1.1

Development stage
Unknown
Lead developer
Apurano Pharmaceuticals
Modality
Small Molecules, Nanoparticles → Drug Delivery Systems
Administration
Oromucosal
01

Overview

CannaXan 701-1.1 (AP701) is an oromucosal cannabinoid spray developed by CannaXan GmbH and manufactured by Apurano Pharmaceuticals. It is a lipid-based nanoparticulate formulation (oil-in-water nano-suspension) produced using the proprietary PuranoTec manufacturing process, which results in particle sizes less than 0.4 µm to enhance bioavailability. The drug contains delta-9-tetrahydrocannabinol (THC) derived from whole decarboxylated flowers of Cannabis sativa L (variety Bedrocan), standardized to 2.2 mg/mL THC and less than 0.15 mg/mL CBD, along with other cannabis constituents including terpenes and flavonoids. As a cannabinoid therapy, it acts as an agonist at cannabinoid receptors (CB1 and CB2). It is being investigated for the treatment of chronic pain and multiple sclerosis, with Phase I trials demonstrating higher bioavailability and better tolerability compared to conventional cannabinoid medications.

Brand names
CannaXan 701-1.1CannaXan701-1.1CannaXan-701-1.1
Other names
AP701AP-701AP 701CannaXan 701CannaXan701CannaXan-701
02

Targets

CNR1 (Cannabinoid receptor 1)

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