Drug intelligence / Profile preview

cantharides + camphor

Development stage
Unknown
Modality
Small Molecules
Administration
Topical
01

Overview

Cantharides + camphor is a topical multi-ingredient pharmaceutical preparation historically used in dermatology, in which **cantharides** provides vesicant activity and **camphor** serves as a counterirritant topical component. Based on the provided context, the therapeutically relevant active blistering component is cantharidin derived from blister beetles, which induces acantholysis in epidermal tissue and has been associated with inhibition of protein phosphatase 1 and protein phosphatase 2A. Preparations containing cantharidin have been used topically for molluscum contagiosum and cutaneous warts; however, the exact named query here refers to the specific combination product term cantharides + camphor rather than a modern standardized single-ingredient cantharidin product.

Other names
cantharides + camphorcantharides camphor
02

Targets

PPP2CA (Serine/threonine-protein phosphatase PP1-alpha catalytic subunit)PP1 (Protein phosphatase 1)PP2A (Protein phosphatase 2A)

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