Drug intelligence / Profile preview

cantharides + white mustard seed

Development stage
Unknown
Modality
Small Molecules
Administration
Topical, Oral
01

Overview

This is a combination of cantharides (the dried bodies or extract of blister beetles, containing the active compound cantharidin) and white mustard seed (Brassica alba). Cantharidin is a terpenoid vesicant historically used as a topical agent for wart removal and molluscum contagiosum, but it is highly toxic if ingested. It acts as a potent blistering agent by causing acantholysis in the skin. White mustard seed has been used in traditional medicine for chest congestion, joint pain, sore throat, and other conditions; its mechanism involves mild antibacterial activity due to certain phytochemicals. There is no strong scientific evidence supporting the efficacy of this combination for any specific indication. Both components are known irritants when applied topically or ingested in large amounts[3][4][5].

02

Targets

PP1 (Protein phosphatase 1)PP2A (Protein phosphatase 2A)

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