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capecitabine + docetaxel + trastuzumab

Development stage: Unknown
Lead developer: Roche
Modality: Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Administration: Oral, Intravenous

Overview

This combination involves **capecitabine**, a tumor-activated oral fluoropyrimidine; **docetaxel**, a taxane chemotherapy drug; and **trastuzumab**, a monoclonal antibody targeting HER2-positive cancers. It is used in the treatment of HER2-positive advanced gastric cancer and metastatic breast cancer. The combination aims to enhance efficacy by targeting different pathways involved in cancer progression.

Targets

TUBB (Tubulin (alpha and beta subunits))TS (Thymidylate synthase)

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