capsaicin + menthol + methyl salicylate

Capsaicin + menthol + methyl salicylate is a topical combination drug used for the temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, strains, sprains, muscle soreness, and related conditions. - **Capsaicin** acts by depleting substance P from sensory nerve endings in the skin, which reduces pain signal transmission. - **Menthol** provides a cooling sensation by activating cold-sensitive TRPM8 receptors on the skin; this counter-irritant effect distracts from deeper musculoskeletal pain. - **Methyl salicylate** is a rubefacient that increases blood flow to the area and also acts as a counter-irritant through vasodilation and mild local irritation. The combination is available over-the-counter (OTC) in various creams or ointments. It does not treat underlying causes but provides symptomatic relief. These products are generally considered safe when used as directed but can cause local skin reactions such as burning or irritation; rare cases of serious burns have been reported with high concentrations or improper use[3][6]. The product should not be applied to broken or irritated skin.

Brand names

Dendracin NeurodendraxcinVolitraBestnacOmni HotXylogesicWoriheal MaxxEllynacXimiflam PlusMove FitDinonacBlinknac