capsicum annuum fruit extract

Capsicum annuum fruit extract is a natural extract obtained from the fruit of the Capsicum annuum plant, commonly known as chili pepper or paprika. It contains various bioactive components, most notably capsaicinoids (such as capsaicin and dihydrocapsaicin), carotenoids, and other phytochemicals. Its mechanism of action is primarily attributed to capsaicin, a selective agonist of the transient receptor potential vanilloid 1 (TRPV1) receptor, which is involved in nociception (pain transmission). Capsaicin overstimulates TRPV1 receptors on sensory neurons, leading to desensitization and an analgesic effect. Beyond analgesia, C. annuum fruit extract and its constituents exhibit antioxidant, anti-inflammatory, antimicrobial, antifungal, and antidandruff activities, and may have metabolic and cardiovascular effects (as anti-obesity, antihypertensive, lipid-lowering agents) through multiple mechanisms such as activation of AMP-activated protein kinase (AMPK), inhibition of pancreatic and lipoprotein lipase, modulation of adipokines, and interference with signaling pathways involved in cellular metabolism, apoptosis, and inflammation. It is used in cosmetics, as a food additive/flavoring, in dietary supplements, and in topical medicinal preparations for the relief of muscle pain and some dermatological uses[1][2][5][6].

Other names

capsicum annuum extractred pepper extractchili pepper extractpaprika extract