Drug intelligence / Profile preview

CAR-507

Development stage
Preclinical
Lead developer
Carmel Biosciences
Modality
Small Molecules
Administration
Oral
01

Overview

CAR-507 is an investigational oral liquid formulation of the calcium channel blocker amlodipine, developed by Carmel Biosciences using its proprietary Bio-Liquid technology. Currently in the Pre-IND stage of development, CAR-507 is designed to provide a stable, ready-to-use liquid alternative to traditional amlodipine tablets. This formulation is primarily intended for patients with hypertension or angina who have difficulty swallowing (dysphagia), such as the elderly or post-stroke patients, and aims to ensure consistent dosing and improved patient compliance. The development follows the FDA 505(b)(2) regulatory pathway, which allows for the approval of new formulations of previously approved drugs.

Other names
Amlodipine Bio-Liquid
02

Targets

CACNA1S (Voltage-dependent L-type calcium channel subunit alpha-1S)CACNA1C (Voltage-dependent L-type calcium channel subunit alpha-1C)CACNA1D (Voltage-dependent L-type calcium channel subunit alpha-1D)

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