Drug intelligence / Profile preview

CAR-iNK 004

Development stage
Preclinical
Lead developer
Cartherics
Modality
CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies, Lymphokine-Activated Killer Cells → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies, iPSCs → Pluripotent Stem Cells → Stem Cell Therapies → Cell Therapies
Administration
Intravenous
01

Overview

CAR-iNK 004 is an investigational cell therapy consisting of natural killer (NK) cells derived from induced pluripotent stem cells (iPSCs) and engineered with a chimeric antigen receptor (CAR). Developed by ThinkingBiomed, the candidate is part of a pipeline utilizing a proprietary iPSC-to-NK differentiation platform to create standardized, off-the-shelf immunotherapies. While the specific tumor-associated antigen targeted by CAR-iNK 004 has not been disclosed, the program is intended for the treatment of various malignancies, including solid tumors like lung, liver, and colorectal cancers, as well as hematological cancers such as B-cell lymphoma. It is currently in the early research and preclinical development stage.

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