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CAR-ThyTreg

Development stage: Preclinical
Lead developer: THYTECH
Modality: CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
Administration: Intravenous

Overview

CAR-ThyTreg is an investigational cell therapy being developed by ThyTech, in partnership with Farmalíder, for the treatment of autoimmune and inflammatory disorders. The therapy utilizes thymus-derived regulatory T cells (ThyTregs) that have been genetically engineered to express a Chimeric Antigen Receptor (CAR). This modification is designed to enable antigen-directed immunomodulation, allowing the Tregs to localize and exert suppressive effects specifically at sites of inflammation or autoimmune activity. Unlike conventional CAR-T therapies that target cells for destruction, CAR-ThyTregs aim to restore immune tolerance and suppress overactive immune responses. The program is currently in the preclinical stage of development, with specific CAR targets and exact indications remaining undisclosed.

Other names: CAR-engineered thymus-derived regulatory T cellsThyTech CAR-ThyTreg

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