carbenoxolone sodium

Carbosan is a topical gel formulation of carbenoxolone sodium, a synthetic derivative of glycyrrhetinic acid (found in licorice). Developed and marketed by Rowa Pharmaceuticals, it is primarily used for the local treatment of mouth ulcers and cold sores (herpes labialis). Carbenoxolone possesses significant anti-inflammatory and cytoprotective properties, which help to reduce pain and promote the healing of damaged mucous membranes and skin. Its mechanism involves the inhibition of enzymes responsible for corticosteroid metabolism, thereby enhancing local anti-inflammatory effects, and it is also known to act as a gap junction blocker. The product is typically applied topically to the affected area at the first sign of symptoms.

Brand names

CarbosanHerpesan

Other names

carbenoxolone sodiumcarbenoxolonedisodium 3-beta-(3-carboxypropionyloxy)-11-oxoolean-12-en-30-oate