carbinoxamine + pseudoephedrine

Carbinoxamine + pseudoephedrine is a combination drug used for the **symptomatic treatment of allergies and nasal congestion**, commonly administered as an oral syrup or tablet. **Carbinoxamine** is a first-generation antihistamine of the ethanolamine class, competing with histamine for H1 receptor binding to reduce allergic symptoms, and possesses notable anticholinergic and sedative properties. **Pseudoephedrine** is a sympathomimetic amine acting as a nasal decongestant by stimulating alpha-adrenergic receptors, resulting in vasoconstriction in the nasal mucosa and thereby relieving congestion. The combination allows for immediate antihistaminic relief (carbinoxamine) and sustained decongestant effect (pseudoephedrine) over up to twelve hours. Primary indications include **allergic rhinitis** and other conditions associated with nasal allergy and congestion[1][8][9][10].

Brand names

Rondec

Other names

carbinoxamine maleate + pseudoephedrine hydrochloride