Drug intelligence / Profile preview

carbocisteine lysine salt

Development stage
Phase 1
Lead developer
Dompé
Modality
Small Molecules
Administration
Oral
01

Overview

Carbocysteine lysine salt (also known as carbocisteine lysine) is a mucolytic agent primarily developed and marketed by Dompé for the treatment of respiratory disorders characterized by excessive or viscous mucus. It is a salt form of carbocisteine (S-carboxymethyl-L-cysteine) combined with the amino acid L-lysine, a formulation designed to enhance solubility and improve gastric tolerability compared to the base molecule. The drug acts by reducing the viscosity of bronchial secretions through the cleavage of disulfide bonds in mucoproteins, thereby facilitating expectoration and improving airway clearance. It is widely used in the management of chronic obstructive pulmonary disease (COPD), acute and chronic bronchitis, and other upper and lower respiratory tract infections.

Brand names
Fluifort
Other names
carbocysteine lysine saltS-carboxymethyl-L-cysteine L-lysine saltcarbocisteine lysine salt monohydrate
02

Targets

KEAP1 (Kelch-like ECH-associated protein 1)MUC2 (Mucin-2)

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