Drug intelligence / Profile preview

carbomycin

Development stage
Unknown
Lead developer
Pfizer
Modality
Small Molecules
Administration
Oral, Injectable
01

Overview

Carbomycin is a crystalline macrolide antibiotic derived from the bacterium Streptomyces halstedii. It exhibits strong inhibitory activity against Gram-positive bacteria and certain Mycoplasma strains. Carbomycin acts by binding to the large subunit of bacterial ribosomes, thereby inhibiting protein synthesis in susceptible organisms. It was historically used primarily in veterinary medicine, especially for treating and preventing chronic respiratory diseases in poultry caused by Mycoplasma gallisepticum and secondary bacterial infections such as Escherichia coli. The structure of carbomycin was first elucidated by Robert Woodward in 1957 and later revised in 1965[1][2][3][5].

Brand names
Magna-terramycin
Other names
magnamycincarbomicinacarbomycinecarbomycinummagnamycin Acarbomycin A
02

Targets

Bacterial 50S ribosomal subunit

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