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carbon-11 acetate
- Development stage
- Phase 3
- Lead developer
- Daniel Vaena
- Modality
- Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
Carbon-11 acetate is a radiopharmaceutical imaging agent used in positron emission tomography (PET) scans. It functions as a metabolic tracer, specifically as a substrate for fatty acid synthesis, a process that is significantly upregulated in certain malignancies, including prostate cancer. Because it is rapidly metabolized and cleared, it offers high-contrast imaging of pelvic tumors without the interference of urinary excretion often seen with FDG-PET. In clinical research led by Daniel Vaena, the tracer is being investigated for its ability to detect lesions and monitor therapeutic response to docetaxel in patients with castrate-resistant prostate cancer (CRPC).
- Other names
- Carbon-11 labeled acetateCarbon11 labeled acetateCarbon 11 labeled acetatePET Acetate
02
Targets
ACS (Acetyl-CoA synthetase)
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