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carboplatin + cisplatin + paclitaxel + pemetrexed
- Development stage
- Preclinical
- Lead developer
- Johnson Matthey
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
A combination chemotherapy regimen consisting of carboplatin, cisplatin, paclitaxel, and pemetrexed. This combination is used in the treatment of non-small cell lung cancer (NSCLC), particularly in patients with locally advanced or metastatic disease. The regimen has shown efficacy in previously treated patients with manageable toxicity profiles.
02
Targets
TS (Thymidylate synthase)DHFR (Dihydrofolate reductase)MicrotubuleDNAGART (GAR transformylase)
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