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Drug intelligence / Profile preview
carboplatin + vinblastine
- Development stage
- Phase 1
- Lead developer
- Johnson Matthey
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
Carboplatin + vinblastine is a chemotherapy combination regimen where both drugs work in different ways to stop the growth of tumor cells. This combination has demonstrated activity in treating metastatic transitional cell carcinoma (TCC) and low-grade gliomas in children. The regimen is generally well-tolerated, though it can cause side effects such as neutropenia.
02
Targets
DNATUBB (Tubulin (alpha and beta subunits))
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