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Carboplatin and Interferon alpha-2a
- Development stage
- Unknown
- Modality
- Vaccines & Immunotherapeutics, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
- Administration
- Intraperitoneal
01
Overview
The combination of carboplatin and interferon alpha-2a has been studied in various clinical settings, particularly for advanced malignancies. This combination therapy has been investigated for its potential synergistic effects in treating different types of cancer. While it has shown some objective responses in certain cancers like advanced malignant melanoma, studies generally suggest it does not provide significant advantages over single-agent therapy and may increase toxicity, leading to significant adverse effects including flu-like symptoms, fatigue, leukopenia, and treatment-related mortality.
02
Targets
DNAIFNAR2 (Interferon alpha/beta receptor subunit 2)
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