carboxymethylated β-glucan

Carboxymethylated β-glucan is a chemically modified, water-soluble derivative of β(1→3)(1→6) glucan, typically sourced from yeast (e.g., Saccharomyces species). This compound demonstrates antioxidant, immunomodulatory, anti-inflammatory, and wound-healing properties. As a derivative of β-glucan, it is more soluble and bioavailable, facilitating oral and topical applications. Carboxymethylated β-glucan has been studied for its ability to reduce oxidative stress (e.g., lowering malondialdehyde), promote immune responses, modulate macrophage activity, and accelerate wound healing. It is also investigated as a component of nanocarriers for antigen delivery and as a sprayable hydrogel for enhancing tissue regeneration and healing, particularly in diabetic models. Its mechanism involves modulation of the innate immune system and antioxidant pathways, though no unique molecular target has been specifically identified[1][2][3].

Brand names

Colpofix

Other names

carboxymethylated β-glucancarboxymethyl-glucanCM-Gcarboxymethyl-β-glucanCMβGcarboxymethylated yeast β-glucan