Drug intelligence / Profile preview

carboxymethylcellulose + glycerin (Sapient Laboratories)

Development stage
Unknown
Lead developer
Sapient Laboratories
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

Zonasoft is an over-the-counter ophthalmic lubricant formulation containing carboxymethylcellulose sodium (0.5% w/v) and glycerin (0.5% w/v), developed and marketed by Sapient Laboratories. It is indicated for the temporary relief of burning, irritation, and discomfort associated with dry eye disease, digital eye strain, and environmental exposure to wind or sun. Carboxymethylcellulose acts as a viscosity-enhancing polymer that binds to corneal epithelial cells to lubricate and protect the ocular surface, while glycerin serves as an ophthalmic demulcent and humectant that attracts and retains moisture, stabilizing the tear film. The formulation also contains stabilized oxychloro complex as an oxidative preservative that breaks down into natural tear components (sodium chloride and water) upon contact with the eye.

Brand names
Zonasoft
Other names
carboxymethylcellulose + glycerincarboxymethylcellulose sodium + glycerin
02

Targets

GLUT1 (Glucose transporter 1)

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