Drug intelligence / Profile preview

carboxymethylcellulose + nepafenac + tobramycin + dexamethasone + tropicamide

Development stage
Unknown
Lead developer
Novartis
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

A combination ophthalmic medication containing five active ingredients: carboxymethylcellulose (an eye lubricant), nepafenac (an NSAID), tobramycin (an aminoglycoside antibiotic), dexamethasone (a corticosteroid), and tropicamide (a mydriatic agent). This combination likely provides multiple therapeutic effects including lubrication for dry eyes, anti-inflammatory action, antibacterial protection, pain relief, and pupil dilation.

02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)mAChR (Muscarinic acetylcholine receptors)23S rRNA (23S ribosomal RNA)30S A-site (Bacterial ribosomal 30S A-site)GR (Glucocorticoid receptor)

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