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carboxymethylcellulose + nepafenac + tobramycin + dexamethasone + tropicamide
- Development stage
- Unknown
- Lead developer
- Novartis
- Modality
- Small Molecules
- Administration
- Ophthalmic
01
Overview
A combination ophthalmic medication containing five active ingredients: carboxymethylcellulose (an eye lubricant), nepafenac (an NSAID), tobramycin (an aminoglycoside antibiotic), dexamethasone (a corticosteroid), and tropicamide (a mydriatic agent). This combination likely provides multiple therapeutic effects including lubrication for dry eyes, anti-inflammatory action, antibacterial protection, pain relief, and pupil dilation.
02
Targets
30S A-site (Bacterial ribosomal 30S A-site)23S rRNA (23S ribosomal RNA)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)GR (Glucocorticoid receptor)mAChR (Muscarinic acetylcholine receptors)
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