Drug intelligence / Profile preview

carboxymethylcellulose sodium

Development stage
Unknown
Lead developer
Advanced Vision Research
Administration
Ophthalmic
01

Overview

TheraTears is a brand of over-the-counter ophthalmic lubricant eye drops primarily used to relieve symptoms of dry eye such as burning, irritation, and discomfort. The active ingredient is sodium carboxymethylcellulose 0.25%, which acts as a mechanical lubricant and moisturizer for the ocular surface[3][4][7]. Its unique hypotonic and electrolyte-balanced formula is designed to replicate healthy natural tears and help restore the tear film's normal osmolarity[3][6]. TheraTears provides immediate, long-lasting relief from dry eye symptoms by supplementing or replacing deficient natural tears. It does not have a pharmacological target but works through physical lubrication and moisture retention on the ocular surface[6]. Developed originally by Dr. Jeffrey P. Gilbard, it has been shown in studies to restore conjunctival goblet cells and corneal glycogen levels[8].

Brand names
TheraTears
Other names
ocular lubricantartificial tearssodium carboxymethylcellulose
02

Targets

GLUT1 (Glucose transporter 1)

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