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Refresh Optive Advanced is an over-the-counter ophthalmic lubricant (artificial tear) formulated for the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun. It contains a triple-action formula with carboxymethylcellulose sodium (5 mg/mL), glycerin (10 mg/mL), and polysorbate 80 (5 mg/mL). The formulation stabilizes the tear film by reinforcing the lipid layer, hydrating and increasing volume in the aqueous layer, and providing advanced lubrication and protection to the mucin layer. It also offers osmo-protection to corneal epithelial cells from excessive salt levels. The product is primarily indicated for dry eye symptoms[2][6][7]. Developed by Allergan.
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