Drug intelligence / Profile preview

carboxymethylcellulose sodium + glycerin + polysorbate 80 (Allergan)

Development stage
Unknown
Lead developer
Allergan
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

Refresh Optive Advanced is a lipid-enhanced lubricant eye drop formulated to relieve dry, burning, and irritated eyes. It features a triple-action formula that lubricates for moisturizing relief, hydrates the eye surface cells, and protects natural tears by reducing tear evaporation. The product supports all three layers of the tear film and is available in both preservative-free single-use vials and multi-dose bottles. Its primary active ingredients are carboxymethylcellulose sodium (0.5%), glycerin (0.9%), and polysorbate 80; these work together to provide temporary relief from symptoms of dry eye due to environmental factors or insufficient tear production[1][2][3][4][5][8]. The mechanism of action is physical lubrication and stabilization of the tear film rather than pharmacological modulation. **Developers:** Allergan **Manufacturers:** Allergan

Brand names
Refresh Optive AdvancedRefresh Optive Advanced Preservative-Free
Other names
Refresh Optive Advanced Lubricant Eye Drops
02

Targets

GLUT1 (Glucose transporter 1)

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