cardamom

Cardamom, derived from the seeds of the plant *Elettaria cardamomum*, is being investigated for its therapeutic potential in managing atopic dermatitis (DOID_3310) due to its anti-inflammatory and immunomodulatory properties. The active constituents of cardamom, including essential oil components like 1,8-cineole (eucalyptol) and the chalcone cardamonin, are thought to modulate the immune response by suppressing the production of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6. In the context of atopic dermatitis, cardamom extracts have demonstrated the ability to inhibit Th2-mediated inflammatory pathways and reduce oxidative stress, which are key drivers of skin barrier dysfunction and chronic inflammation. While primarily used as a spice and dietary supplement, its extracts are being explored in preclinical and pilot studies for their efficacy in reducing skin lesions and systemic inflammatory markers associated with atopic conditions.

Other names

Elettaria cardamomumGreen CardamomTrue Cardamom