Drug intelligence / Profile preview

Cardiostatil

Development stage
Unknown
Lead developer
Aflofarm
Modality
Small Molecules
Administration
Oral
01

Overview

Cardiostatil is a multi-ingredient dietary supplement developed by the Polish pharmaceutical company Aflofarm, designed to support cardiovascular health and maintain healthy blood cholesterol levels. The formulation contains 2.75 mg of monacolin K, a naturally occurring statin-like compound derived from fermented red rice (*Monascus purpureus*), which acts as an HMG-CoA reductase inhibitor. Additional active components include bergamot fruit extract (*Citrus bergamia*) standardized to polyphenols, garlic extract, coenzyme Q10, and vitamins B6 and B12. The product was specifically reformulated to contain less than 3 mg of monacolin K per daily portion to comply with European Union Commission Regulation 2022/860, which restricts higher dosages of monacolin K in supplements due to safety concerns.

Brand names
Cardiostatil
02

Targets

HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)

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