Drug intelligence / Profile preview

Cardiovis Colesterolo

Development stage
Unknown
Lead developer
Bios Line
Modality
Small Molecules
Administration
Oral
01

Overview

Cardiovis Colesterolo is a multi-ingredient nutraceutical food supplement developed by Bios Line and studied by the University Hospital of Ferrara for the management of hypercholesterolemia. It contains a combination of fermented red rice (providing monacolins K, L, M, and N), sweet potato (Ipomoea batatas) tuber extract, mandarin (Citrus reticulata) pericarp extract rich in polymethoxyflavones, Eidrosol (a proprietary blend of olive fruit extract and vitamin E), and coenzyme Q10. The supplement is designed to reduce plasma cholesterol levels, improve endothelial function, and lower inflammatory parameters in subjects with low to moderate cardiovascular risk. Its primary mechanism involves the inhibition of HMG-CoA reductase by monacolins, which are structurally similar to statins, alongside the upregulation of LDL receptor expression and enhancement of nitric oxide production to support vascular health.

Brand names
Cardiovis Colesterolo
02

Targets

HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)

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