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CARELIV
- Development stage
- Unknown
- Lead developer
- Adwin Life Care
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
CARELIV is a hepatoprotective pharmaceutical product developed and marketed by Adwin Life Care. It is a combination therapy typically formulated with silymarin (a standardized extract of flavonolignans from *Silybum marianum*) and L-ornithine L-aspartate (LOLA). The drug is indicated for the treatment and management of various liver conditions, including fatty liver, chronic hepatitis, and liver cirrhosis. Silymarin acts as an antioxidant and membrane stabilizer, promoting hepatocyte regeneration by stimulating RNA polymerase I, while LOLA facilitates ammonia detoxification by increasing the activity of the urea cycle and glutamine synthesis. CARELIV is available in oral dosage forms such as tablets and syrup and is approved for use in India.
- Brand names
- CARELIV
- Other names
- CARELIVsilymarin + l-ornithine l-aspartate
02
Targets
Pol I (RNA polymerase I)CPS1 (Carbamoyl phosphate synthetase I)GLUL (Glutamine synthetase)
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