CaReS

**CaReS** is a matrix-associated autologous chondrocyte implantation product for repair of focal chondral and osteochondral articular-cartilage defects, particularly in the knee. The patient’s own articular chondrocytes are isolated, expanded and embedded in a three-dimensional type I collagen hydrogel, which is surgically implanted into the prepared cartilage defect and fixed in place. The collagen matrix provides a structural environment for the implanted chondrocytes, supporting cartilage regeneration and formation of hyaline-like cartilage. CaReS has been developed by Ars Arthro and Arthro Kinetics; the Japanese development version is designated IK-01 and is being developed by CynosBio for knee cartilage injury and knee osteoarthritis.

Brand names

CaReS

Other names

CaReS-2StepCaReS2StepCaReS 2StepCartilage Regeneration System