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Carica papaya seed aqueous extract is a botanical preparation derived from the seeds of the unripe pawpaw fruit (*Carica papaya*). It is traditionally used in folk medicine for the management of diabetes mellitus. The extract's therapeutic potential is attributed to its ability to inhibit key enzymes involved in carbohydrate metabolism, specifically alpha-amylase and alpha-glucosidase, thereby potentially reducing glucose absorption. Furthermore, it demonstrates antioxidant activity by protecting pancreatic cells from lipid peroxidation. Research indicates that while the seed extract is effective individually, it may exhibit synergistic effects when combined with extracts from the flesh and peel of the fruit.
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