carmellose sodium

Carboxymethylcellulose sodium (carmellose sodium) is a high-molecular-weight, water-soluble cellulose derivative used primarily as an ophthalmic lubricant. It is a mucoadhesive polymer that increases the viscosity of the tear film and prolongs the retention time of the solution on the ocular surface. By binding to corneal epithelial cells, it provides a protective barrier and promotes surface hydration, offering temporary relief from burning, irritation, and discomfort associated with dry eye disease (keratoconjunctivitis sicca) or environmental exposure to wind and sun. Sanjar Pharma manufactures this agent as a generic sterile ophthalmic solution, often formulated to mimic the properties of natural tears.

Brand names

RefreshCelluviscOptiveRefresh TearsRefresh Plus

Other names

carboxymethylcellulose sodiumsodium carboxymethylcelluloseCMCcarboxymethyl cellulose sodiumcarmelloseE466E-466E 466