carpronium chloride

Carpronium chloride is a synthetic quaternary ammonium compound and a direct-acting muscarinic acetylcholine receptor agonist. Originally developed in Japan by Daiichi Pharmaceutical, it is primarily used as a topical hair growth stimulant to treat various forms of alopecia, including alopecia areata and androgenetic alopecia, as well as vitiligo vulgaris and seborrhea sicca. By mimicking parasympathetic activity, carpronium chloride dilates local capillaries and enhances blood circulation in the scalp, thereby improving nutrient and oxygen delivery to hair follicles and promoting hair regrowth. It is marketed in Japan under brand names such as Furozin and the over-the-counter Caloyan series. An oral formulation was historically marketed under the brand name Actinamin for the treatment of gastroptosis, but has since been discontinued.

Brand names

ActinaminCaloyanFroginFurozin

Other names

(3-carboxypropyl)trimethylammonium chloride methyl ester(4-methoxy-4-oxobutyl)-trimethylazanium chloride3-carboxy-N,N,N-trimethyl-1-propanaminium chloride methyl estercarpronium chloride hydratecloruro de carproniog-butyrobetaine chloride methyl estermethyl N-trimethyl-g-aminobutyrate chlorideカルプロニウム塩化物