carrageenan + povidone-iodine

Carrageenan + povidone-iodine is a topical combination therapy being investigated for the treatment of early-stage COVID-19 infection. The regimen consists of an iota-carrageenan nasal spray and a povidone-iodine (PVP-I) mouthwash or gargle. Iota-carrageenan is a sulfated polysaccharide derived from red marine algae that acts as a physical barrier by binding to and trapping SARS-CoV-2 virions, thereby preventing their attachment and entry into host cells in the nasal mucosa. Povidone-iodine is a well-established broad-spectrum antiseptic that provides rapid virucidal activity in the oral cavity and oropharynx through the oxidation of essential viral proteins and nucleic acids. This dual-action topical approach is designed to reduce the viral load at the primary sites of infection, potentially alleviating symptoms, shortening the duration of illness, and reducing the risk of disease progression and transmission in patients within 120 hours of symptom onset.

Other names

carrageenan + polyvinylpyrrolidoneiota-carrageenan + povidone-iodinecarrageenan + PVP-Iiota-carrageenan + polyvinylpyrrolidone