Drug intelligence / Profile preview

Carteolol

Development stage
Approved
Lead developer
Santen Pharmaceutical
Modality
Small Molecules
Administration
Ophthalmic, Oral
01

Overview

Carteolol is a nonselective beta-adrenergic antagonist (beta-blocker) primarily used in ophthalmology to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It acts by blocking both beta1 and beta2 adrenergic receptors in the ciliary body of the eye, leading to decreased production of aqueous humor and thus reduced intraocular pressure. Carteolol has partial agonist (intrinsic sympathomimetic) activity but lacks significant membrane-stabilizing effects. It is generally administered as an ophthalmic solution and may be used alone or with other agents for glaucoma management. Systemically, carteolol has also been used for arrhythmia, angina, and hypertension[1][2][4][6][8].

Brand names
OcupressCartrol
Other names
Carteololumcartéolol
02

Targets

ADRB1 (β1)ADRB2 (β2)

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