Drug intelligence / Profile preview

Casea S

Development stage
Unknown
Lead developer
FHI 360
Modality
Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Devices → Device-based Delivery → Drug Delivery Systems, Small Molecules
Administration
Subdermal
01

Overview

Casea S is a biodegradable, long-acting contraceptive implant designed to provide reversible contraception for 18–24 months. It releases etonogestrel, a well-characterized synthetic progestin used in existing contraceptive implants, via subdermal pellets. The unique feature of Casea S is its biodegradability—after the active period, the implant dissolves in the body and does not require surgical removal by a healthcare provider. This innovation aims to improve access and convenience for users, especially in settings where follow-up care may be limited. The product is currently being evaluated in Phase 1 clinical trials for pharmacokinetics, removability (if needed), safety, and tolerability[1][2][4][5][6].

Brand names
Casea S
Other names
Casea S biodegradable contraceptive implant
02

Targets

PR (Progesterone receptor)

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