Drug intelligence / Profile preview

casein hydrolysate

Development stage
Unknown
Modality
Recombinant Proteins and Enzymes, Peptides
Administration
Oral
01

Overview

Casein hydrolysate is a mixture of peptides produced by the enzymatic or chemical breakdown (hydrolysis) of the milk protein casein. It is used as a dietary supplement and functional food ingredient due to its bioactive properties. Casein hydrolysate contains various bioactive peptides that have demonstrated antihypertensive, anti-inflammatory, antioxidant, and antiallergy effects. Its primary mechanism of action involves inhibition of angiotensin I-converting enzyme (ACE), which leads to reduced formation of vasoconstrictor angiotensin II and results in blood pressure lowering effects. Additional mechanisms include inhibition of renin and endothelin-converting enzyme activities[1][5]. Casein hydrolysate is also used in laboratory culture media for growing fastidious microorganisms[4].

Brand names
NutramigenProgestimil
Other names
casein peptideshydrolyzed casein
02

Targets

REN (Renin)ECE1 (Endothelin-converting enzyme 1)ACE (Angiotensin Converting Enzyme)

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