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Casein hydrolysate is a mixture of peptides produced by the enzymatic or chemical breakdown (hydrolysis) of the milk protein casein. It is used as a dietary supplement and functional food ingredient due to its bioactive properties. Casein hydrolysate contains various bioactive peptides that have demonstrated antihypertensive, anti-inflammatory, antioxidant, and antiallergy effects. Its primary mechanism of action involves inhibition of angiotensin I-converting enzyme (ACE), which leads to reduced formation of vasoconstrictor angiotensin II and results in blood pressure lowering effects. Additional mechanisms include inhibition of renin and endothelin-converting enzyme activities[1][5]. Casein hydrolysate is also used in laboratory culture media for growing fastidious microorganisms[4].
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