Drug intelligence / Profile preview

casuarina equisetifolia pollen extract

Development stage
Unknown
Lead developer
ALK Abelló
Modality
Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Percutaneous, Intradermal
01

Overview

Casuarina equisetifolia pollen extract is a non-standardized, biologic allergenic extract developed and marketed by ALK-Abello, Inc. The active ingredient is derived from the pollen of the *Casuarina equisetifolia* tree, also known as the Australian Pine or Beefwood tree. First approved in the United States in 1965, it is administered via subcutaneous injection. The product is used for both diagnostic allergy testing and for therapeutic hyposensitization (allergen immunotherapy) in patients with confirmed allergies to this specific pollen. The mechanism of action involves modulating the patient's immune response to the allergen, inducing a state of tolerance. This is achieved by promoting a shift in T-cell responses and stimulating the production of blocking IgG antibodies, which reduces the IgE-mediated allergic reaction upon natural exposure to the pollen.

Other names
Australian Pine pollen extractBeefwood pollen extractShe-oak pollen extractWhistling-pine pollen extractHorsetail tree pollen extractCasuarina equisetifolia pollen

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