Drug intelligence / Profile preview

CAT-09-833

Development stage
Preclinical
Lead developer
Catalent
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

CAT-09-833 is a preclinical **MUC1-targeting antibody-drug conjugate** being developed by Catalent using its SMARTag platform for solid tumors, with public descriptions highlighting **platinum-resistant ovarian carcinoma** as the lead indication. Available public-source descriptions characterize it as a tumor-selective anti-MUC1 ADC with encouraging preclinical efficacy and tolerability; however, the exact antibody sequence, payload, linker composition, and precise target epitope details have not been clearly disclosed in the public materials identified. Based on the available information, its intended mechanism is selective binding to **Mucin-1**-expressing tumor cells followed by ADC-mediated delivery of a cytotoxic payload to drive antitumor activity.

02

Targets

MUC1 (Mucin-1 Antigen)

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