Drug intelligence / Profile preview

catechin gallate

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

Catechin gallate is a **flavonoid**, specifically a gallate ester of the flavan-3-ol catechin, and a member of the chemical class *catechin gallates*. It is most commonly found as a constituent of tea leaves, where it occurs at lower concentrations compared to its analogs such as epigallocatechin gallate (EGCG). As a polyphenol, catechin gallate is proposed to exhibit antioxidant, anticarcinogenic, and antimicrobial activities, although direct pharmacological applications in clinical medicine are not established. Its **mechanism of action** is primarily through **antioxidant activity**, which involves scavenging free radicals and potentially modulating signaling pathways associated with oxidative stress and cellular protection[5][9]. It has been studied for various potential health effects, primarily in the context of dietary supplements and functional foods.

Other names
catechin gallatecatechin 3'-O-gallatecatechin 3'-O-gallic acid(2-hydroxy-5-((2R,3S)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl)phenyl) 3,4,5-trihydroxybenzoate[2]
02

Targets

NeuraminidasePTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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