Drug intelligence / Profile preview

cathine

Development stage
Discontinued
Lead developer
Merck
Modality
Small Molecules
Administration
Oral
01

Overview

Cathine is a psychoactive drug with stimulant properties belonging to the phenethylamine and amphetamine chemical classes. It is found naturally in the khat plant (Catha edulis) and acts as a central nervous system stimulant. Cathine has been used for its euphoric and appetite-suppressing effects but is not approved for medical use in most countries. In the United States it is classified as a Schedule IV controlled substance[1][2][3]. Its mechanism of action involves promoting norepinephrine release from nerve terminals[4].

Brand names
AlvalinAntiadipositum X-112 T
Other names
d-norpseudoephedrine(+)-norpseudoephedrinecathinacathinumd-cathined-nor-psi-ephedrinekatinepseudonorephedrinepsi-norephedrine
02

Targets

NET (Norepinephrine Transporter)DAT (Dopamine plasma membrane transport protein)

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