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Drug intelligence / Profile preview
cattle encephalon glycoside and ignotin
- Development stage
- Phase 4
- Lead developer
- Jilin Sihuan Pharmaceutical
- Modality
- Recombinant Proteins and Enzymes, Peptides
- Administration
- Intramuscular, Intravenous
01
Overview
Cattle encephalon glycoside and ignotin (CEGI) is an animal-derived neuroprotective drug approved in China for the treatment of central and peripheral nerve injuries, including stroke, cerebral infarction, and diabetic neuropathy. It is a compound preparation consisting of rabbit muscle extract and cattle brain gangliosides, containing active components such as ganglioside GM1, carnosine, polypeptides, free amino acids, and nucleic acids. CEGI exerts multi-target neuroprotective effects by promoting nerve repair and regeneration, reducing neuroinflammation, inhibiting oxidative stress and apoptosis, and improving cognitive function.
- Brand names
- OudimeiOudimi欧迪美
- Other names
- CEGICEGI injectioncattle encephalon glycoside and ignotincattle encephalon glycoside and ignotin injectioncerebroside carnosinecerebroside carnosine injectioncerebroside-carnosinecerebroside-carnosine injection
02
Targets
Aβ (Amyloid-beta peptides and aggregates)BCL-2 (BCL-2 family)GDNF (Glial cell line-derived neurotrophic factor)NF-κBTLR4 (Toll-like receptor 4)
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