Drug intelligence / Profile preview

cattle encephalon glycoside and ignotin (Sihuan Pharmaceutical)

Development stage
Unknown
Lead developer
Jilin Sihuan Pharmaceutical
Modality
Peptides, Recombinant Proteins and Enzymes
Administration
Intramuscular, Intravenous
01

Overview

Cattle encephalon glycoside and ignotin (CEGI) is an animal-derived neuroprotective drug approved in China for the treatment of central and peripheral nerve injuries, including stroke, cerebral infarction, and diabetic neuropathy. It is a compound preparation consisting of rabbit muscle extract and cattle brain gangliosides, containing active components such as ganglioside GM1, carnosine, polypeptides, free amino acids, and nucleic acids. CEGI exerts multi-target neuroprotective effects by promoting nerve repair and regeneration, reducing neuroinflammation, inhibiting oxidative stress and apoptosis, and improving cognitive function.

Brand names
OudimeiOudimi欧迪美
Other names
CEGICEGI injectioncattle encephalon glycoside and ignotincattle encephalon glycoside and ignotin injectioncerebroside carnosinecerebroside carnosine injectioncerebroside-carnosinecerebroside-carnosine injection
02

Targets

BCL-2 (BCL-2 family)NF-κBGDNF (Glial cell line-derived neurotrophic factor)TLR4 (Toll-like receptor 4)Aβ (Amyloid-beta peptides and aggregates)

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